Merrifield Resin. Loading capacity: 1.2-1.6 mmol/g

Chloromethyl Resin

Merrifield Resin, also known as Chloromethyl Resin, is the original solid support used in R. B. Merrifield�s pioneering solid-phase peptide synthesis (SPPS). It is a polystyrene matrix crosslinked with divinylbenzene (DVB) and functionalized with reactive chloromethyl groups, enabling attachment of the first amino acid through a stable benzyl ester bond. This resin remains a classical choice for synthesizing peptides with C-terminal free acids.

Product

Merrifield Resin

Catalog No.

PR1003

Cas no. 

9003-70-7

Matrix/Backbone:

Polystyrene crosslinked with 1% DVB

Degree of cross-linking (% DVB) 

1%

Substitution (mmol/g) 

1.2-1.6 mmol/g

Mesh Size

100 - 200

Apperance

Pale or slight yellow beads

Loss on drying (%) 

≤ 2.0

Degree of swelling in DCM (ml/g) 

5.0 - 9.0

Degree of swelling in DMF (ml/g)

4.0 - 8.0

Storage

02 - 04 

Size 

Price

Discount

Global stock

5 g

Enquiry

NA

In-stock

25 g

Enquiry

NA

In-stock

100 g

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NA

In-stock

others

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NA

In-stock

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