Chloromethyl Resin. Loading capacity: 0.4-0.8 mmol/g
Synonym(s): Merrifield Resin
Product information
Merrifield Resin, also known as Chloromethyl Resin, is the original solid support used in R. B. Merrifieldโs pioneering solid-phase peptide synthesis (SPPS). It is a polystyrene matrix crosslinked with divinylbenzene (DVB) and functionalized with reactive chloromethyl groups, enabling attachment of the first amino acid through a stable benzyl ester bond. This resin has historically been the standard support for the synthesis of peptide acids via the Boc strategy.
Product | Chloromethyl Resin |
Catalog No. | PR1001 |
Cas no. | 9003-70-7 |
Matrix/Backbone: | Polystyrene crosslinked with 1% DVB |
Degree of cross-linking (% DVB) | 1% |
Substitution (mmol/g) | 0.4-0.8 mmol/g |
Mesh Size | 100 - 200 |
Apperance | Pale or slight yellow beads |
Loss on drying (%) | โค 2.0 |
Degree of swelling in DCM (ml/g) | 5.0 - 9.0 |
Degree of swelling in DMF (ml/g) | 4.0 - 8.0 |
Storage | 02 - 04 |
Size | Price | Discount | Global stock |
5 g | Enquiry | NA | In-stock |
25 g | Enquiry | NA | In-stock |
100 g | Enquiry | NA | In-stock |
others | Enquiry | NA | In-stock |
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